Modifying Enzymes
New England Biolabs, Inc. Thermostable FEN1 – 1600 units
Thermostable Flap Endonuclease 1, FEN1, catalyzes the cleavage of 5 DNA flaps from branched double stranded DNA substrates, creating a 5' phosphate terminus. FEN1 products can be ligated by DNA ligase to create double stranded DNA. In vivo, FEN1 is an essential component of the Okazaki fragment maturation pathway, and also plays a role in base excision repair.
Chem-Impex International, Inc. a-Chymotrypsin from bovine pancreas | 9004-07-3 | MFCD00130481 | 1G
a-Chymotrypsin from bovine pancreas, 9004-07-3, MFCD00130481, 1G
Cell Biolabs Inc OxiSelect™ Myeloperoxidase Chlorination Activity Assay Kit (Colorimetric), 200 assays
Myeloperoxidase (MPO) is a peroxidase enzyme highly expressed in stimuated neutrophil granulocytes. The enzyme has two activities: chlorination and peroxidation. Its chlorination activity produces hypochlorous acid (HOCl), a reactive oxygen intermediate that helps the neutrophils kill microbes. Cell Biolabs' OxiSelect™ Myeloperoxidase Chlorination Activity Assay Kit is a quantitative, colorimetric assay for measuring the chlorination activity of myeloperoxidase within a sample. Each kit provides sufficient reagents for 200 assays including standards and unknown samples.
New England Biolabs, Inc. PNGase F, Recombinant – 15000 units
PNGase F is the most effective enzymatic method for removing almost all N-linked oligosaccharides from glycoproteins. PNGase F, Recombinant is a recombinant amidase, which cleaves between the innermost GlcNAc and asparagine residues of high mannose, hybrid, and complex oligosaccharides.
Qiagen Beverly Inc T4 DNA LIGASE
DNA Ligase; T4 DNA Ligase; Conc. 120,000 U/ml; 150,000 U; incl. 10X buffer
Aldevron SpCas9 Nuclease, 0.25mg
0.25mg dispense of SpCas9 Nuclease. Aldevron provides Research-grade Cas9 nucleases via Fisher Scientific for use in development work as well as standard cGMP products for clinical studies when ordered direct.
Functional Performance
•Ready to use for electroporation or transfection
•Extensive QC panels
•10 mg/mL formulation
Aldevron SpyFi Cas9 Nuclease, 0.25mg
0.25mg dispense of SpyFi Cas9 Nuclease. From basic research to clinical applications, our SpyFi Cas9 Nuclease delivers greater editing efficiency and reduced off-target effects without loss of on-target activity to help accelerate your CRISPR-Cas9 gene editing program. SpyFi Cas9 Nucleases are available at Research-Grade through Fisher, or across all quality grades (Research Grade or GMP) directly through Aldevron.
SpyFi Cas9 Nuclease is uniquely positioned to satisfy a wide range of needs from basic research to clinical applications. When used in combination with effective guide, target site and double-stranded DNA cut strategies, SpyFi Cas9 Nuclease delivers greater editing efficiency, higher fidelity and less off-target activity than wild-type SpCas9 nuclease.
Functional Performance
•Reduced off-target effects
•Ready to use for electroporation or transfection
•10 mg/mL formulation for ease of use
Worthington Biochemical Corporation STEMXYME 1 COLLAGENAS 50MG
A specialized combination of Animal Origin-Free Clostridium histolyticum collagenase (Code: CLSAFB) and animal origin free Bacillus polymyxa neutral protease with a minimum of 250 CLS units and 1,000 caseinase units per mg dry weight. Designed for stem cell and other primary cell isolations and bioprocessing applications where introduction of potential animal derived pathogens must be prevented. 2593-92-3
Abcam Bano x antrone dihydrochloride (AQ4N), Topoisomerase II inhibitor, 10MG
MW 517.4 Da, Purity >97%. Bioreductive AQ4 precursor. Topoisomerase II inhibitor. Converts under hypoxia to DNA-affinic mitoxantrone (ab141041) structural analog. Induces DNA intercalation. Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
MINNEBIO LLC Ultra-Active Nuclease (Serratia marcescens Nuclease, EC 3.1.30.2) Benzonase Alternative Purity 98%10 kU.
Ultra-Active Nuclease is extensively utilized across biopharmaceutical and academic research settings for its ability to streamline nucleic acid removal and improve sample processing. Beyond standard cell lysate applications, it enhances protein purification workflows by reducing nucleic acid contamination, facilitates viral vector and vaccine production by maintaining low-viscosity solutions, and supports antibody development by ensuring cleaner preparations for downstream analyses. Its broad compatibility allows use under diverse conditions, including high-salt buffers, detergents, or partially denatured samples, making it highly versatile for complex biological systems. Widely trusted by leading pharmaceutical companies, top research institutes, and university laboratories worldwide, this enzyme delivers reproducible results, contributes to higher assay accuracy, and reduces processing time in critical experimental and manufacturing workflows.
Sigma Aldrich Fine Chemicals Biosciences Elastase from porcine panc10MG
ELASTASE Elastase from porcine panc10MG
Biotium Double Stranded DNA (dsDNA)(AE-2), 0.2mg/mL
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds be